Frontal fibrosing alopecia. Authoritative facts about the skin from DermNet New Zealand. Frontal fibrosing alopecia is a disorder resulting in hair loss at the temples and front of the scalp. Learn about the causes and treatment of FFA. BackgroundFrontal fibrosing alopecia is considered a particular clinical form of lichen planopilaris that primarily involves the scalp hair over the frontal hai.
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Frontal fibrosing alopecia usually affects post-menopausal women over the age of In the frontal area, the loss may be more marked behind a preserved frontal hairline. The finding of gross interfollicular scarring, panfollicular lymphocytic inflammation, or involvement of the interfollicular alopecoa in a biopsy should prompt a search for an alternate form of scarring alopecia that may mimic FFA.
Signs of cutaneous lupus on sun-exposed sites is often helpful in the differential. What is frontal fibrosing alopecia?
The cause of frontal fibrosing alopecia is unknown. The lichenoid reaction in FFA targets and destroys the follicular sheaths and stem cell region, but spares the interfollicular epidermis and also the lower follicle and hair bulb region.
Dermoscopy may also be useful in detecting loss of follicles. This may help frontal fibrosing apopecia become inactive in some people.
British Association of Dermatologists – Patient Information Leaflets (PILs)
This pattern has also followed oophrectomy. Etiology The etiology of FFA remains unknown. The cibrosing of this reaction at the frontal hairline may subsequently trigger a more widespread destruction of the eyebrows and hair follicles at other sites. By the time the medical consultation occurs, the process is often advanced. Approximately half of all cases of FFA also have eyebrow loss; less often there is hair loss in other parts of the body. This leaflet has been written to help you understand more about frontal fibrosing alopecia.
The facial skin specimen showed intense lymphoplasmocytic infiltrate with complete destruction of the follicle and only remnants of the piloerector muscle and sebaceous gland Figure 2 C. Summary Epidemiology Prevalence is unknown.
Elderly women, often years after menopause, represent the main group who present frnotal FFA. Donati, Valente, and Romiti. Where can I get more information?
Sincethere have been several reports of the use of the antidiabetic agent pioglitazone off-label for the treatment of frontal fibrosing alopecia. The histopathological features are identical to those of lichen planopilaris. What if I need a wig? Proximities, such as inframandibular and retroauricular areas, may also be affected; this may help differentiate FFA from photodamage.
Frontal Fibrosing Alopecia
J Am Acad Dermatol. This may occur with frontal fibrosing akopecia also contributing to hair loss. Currently, the combination of finasteride and topical minoxidil particularly in women with combined female pattern hair loss or hydroxychloroquine are the main treatments that appear to help stabilize FFA.
Biopsies of both the frontal hairline and preauricular region were performed. Diagnosis confirmation The differential diagnosis of FFA includes: Scalp biopsy and serological tests for lupus are helpful in difficult cases. How to get funding?
Frontal fibrosing alopecia
Whether current therapy ultimately alters the course or severity of FFA has not been established. Br J Dermatol ; They can help to relieve the symptoms and redness of the scalp. Create a personal account to register for email alerts with links to free full-text articles. Biopsy of skin papules may show a lichenoid pattern of inflammationfibrosing alopeciaor sebaceous gland hyperplasia.
Scalp biopsy and bacterial cultures will help to differentiate these cases. If you have any concerns with your skin or its treatment, see a dermatologist for advice.